2026年4月17日，北京大学博雅讲席教授、昌平实验室领衔科学家、生命科学学院邓宏魁课题组在国际学术期刊《细胞》（Cell）上发表了题为“p53 safeguards chemical reprogramming of human somatic cells toward pluripotency”的研究论文。该研究发现，关键肿瘤抑制因子p53在化学重编程中发挥核心保护作用，打破了“p53阻碍细胞 ...

Leuven, 11 March 2025 – Solid tumors often provide a challenging environment for the T cells of our immune system. By reprogramming the metabolism of T cells, scientists at the VIB-KU Leuven Center ...

Cancer incidence rises sharply with age, yet the biological mechanisms that make older patients more vulnerable to treatment failure remain poorly ...

Researchers created hybrid macrophages that support multiple stages of bone healing, including regeneration and ...

A new way of reprogramming our immune cells to shrink or kill off cancer cells has been shown to work in the otherwise hard to treat and devastating skin cancer, melanoma. The discovery demonstrates a ...

One promising strategy to remuscularize the injured heart is the direct cardiac reprogramming of heart fibroblast cells into cardiomyocytes. Researchers have identified TBX20 as the key missing ...

Solid tumors often provide a challenging environment for the T cells of our immune system. By reprogramming the metabolism of T cells, scientists at the VIB-KU Leuven Center for Cancer Biology and ...

In summary, macrophages secrete IFN-β, activating the IFN-β-IFNAR-p-STAT1 axis in MICFs, leading to increased secretion of CCL2/7/12 chemokines and subsequent recruitment of more IFN-β-secreting ...

Aging is a complex process that has long puzzled scientists. A recent study published in Engineering proposes a new theory called pro-aging metabolic reprogramming (PAMRP), which could change our ...

Billions of dollars are pouring into longevity startups as a growing body of research shows that aging might not be as inevitable as we assumed. Now, a startup claims to have reached a major milestone ...